gardenartus 12,687 Report post Posted September 28, 2019 The clinical endocannabinoid deficiency hypothesis states that impairments in the endocannabinoid system (ECS) are responsible for a multitude of medical conditions. This could involve reduced levels of endocannabinoids, but also impaired receptor signaling. The cannabinoid CB2 receptor is critical for limiting inflammation. Your risk of many immune diseases may be heightened if you have this genetic variant. 9 Inflammatory Diseases Linked To Impaired Cannabinoid CB2 Receptor 2 Quote Share this post Link to post Share on other sites